Weight Loss Agents

Sibutramine

Drug Class: Weight Loss Agents

Sibutramine (trade names Goldline, Meridia, Reduxin) is a pharmacological means for suppressing appetite during weight loss.

Structurally, sibutramine is similar to the class of amphetamines, although it does not possess their biological properties. Sibutramine, a central action drug, is a reuptake inhibitor of serotonin (53%), norepinephrine (54%) and dopamine (16%), which increases the level of these mediators in the intersynaptic space. Thus, increasing the concentration of serotonin in the center of hunger and saturation, the drug suppresses the appetite.

Sibutramine may cause a change (improve) mood, because the control of energy homeostasis and mood often used the overlapping parts of the brain (eg, serotonergic) th

We added a novelty, a new product of 2018: a combined package of Sibutramine + Metformin. Reduxin Met

Sibutramine as a drug

A high level of drug control in the West generates false rumors that Sibutramine is a drug. This drug does not cause addiction, since it does not increase the release of dopamine from synapses, and a high level of control is associated with the unauthorized use of Sibutramine as a means of losing weight, which can only speak of high efficiency.

Doses of Sibutramine and a way of using it for los

The average dose of Sibutramine is 10 mg once a day in the first half of the day, if it is not enough after a few days of use, the dose can be raised to 15 mg per day. Usually, 6 months after the start of treatment and until the drug is stopped, appetite normalizes, and body weight is set on a plateau. Do not exceed the dose, because often this is associated with side effects and complications. Admission is carried out in combination with a low-calorie diet and exercise. After discontinuation of the drug is often observed a set of lost weight. Sibutramine is an effective means of reducing body weight and food intake during treatment for a short period of time (6-12 months), its effectiveness decreases with prolonged intake of the drug (> 1 year)

Sibutramine in the US

In the US, it is classified as a means of causing dependence, although it is not. The only reason for the control is abuse as an anorexic, getting it for the first time under the prescription of a doctor, people then begin to continue unauthorized reception for weight loss themselves.

Side effects of sibutramine

Relatively often there are side effects from the cardiovascular system (about 10%): an increase in blood pressure by 2-20 mm Hg, an increase in the heart rate by 3-20 beats / min. In 2010, the FDA expressed concern about the high risk of heart disease and strokes with Sibutramine in people with cardiovascular disease. There are also side effects associated with its noradrenergic stimulation of the hypothalamus of the mechanisms regulating appetite and sympathomimetic properties: dry mouth, nausea, taste change, digestive disorders, constipation, insomnia, anxiety, algomenorrhea, pain in muscles and joints, difficulty urinating, violation view.

At a young age, in the absence of heart disease and blood vessels, Sibutramine is considered a safe drug. If side effects occur, after withdrawal all symptomatology disappears without harm to health. Serious complications are rare.

Scientists believe that a person is at greater risk of being obese than with Sibutramine.

The owner of the registration certificate: PROMOMED REDUXIN HOLDINGS (Cyprus) LIMITED, LLC (Cyprus)
Manufacturer: Ozon (Russia)

Marketing on the territory of the Russian Federation:
PROMOMED DM LLC (Russia)
Agency:
PROMOMED RUS LLC

Price:
10 mg 30 caps = 60 EUR
15 mg 30 caps = 75 EUR
10 mg 60 caps = 100 EUR
15 mg 60 caps = 130 EUR