Gonadorelin for sports and for male enhancement

Gonadorelin (synonyms: gonadoliberin, gonadotropin-releasing hormone) is a natural hormone that causes an increase in the secretion of gonadotropins: FSH (follicle-stimulating hormone) and LH (luteinizing hormone), which in turn increase the secretion of testosterone. Currently, synthetic analogues of gonadorelin have appeared, which have begun to be used in bodybuilding. In fact, it is a replacement for chorionic gonadotropin, while not having any special advantages over it in bodybuilding. In medicine, GnRH is used to treat endometriosis, uterine fibrosis, infertility and prostate cancer.

Physiology:
The hypothalamus releases several hormonal substances, one of which is gonadorelin, which is a decapeptide in structure. Gonadorelin, in turn, acts on the receptors of the anterior pituitary gland, causing it to release gonadotropins (luteinizing hormone and follicle-stimulating hormone), which in turn regulate the release of male sex hormones (androgens) by the testes.

The secretion of these hormones is pulsating with a frequency of about 1-2 times per hour. This secretion is regulated by a feedback mechanism by other hormonal substances. Hormones such as estrogens, testosterone and anabolic steroids suppress the hypothalamus-pituitary-testes axis, so the production of its own testosterone decreases.

The use to Bodybuilding:
In bodybuilding, gonadorelin is used to increase the secretion of its own testosterone according to the first scheme. The drug is administered every 1.5 or 3 hours for 2-4 weeks, the recommended dosage is 100-200 mcg. You should not enter GnRH for a longer time, as this can cause significant suppression of your own testosterone after withdrawal. It is most rational to use gonadoliberin as a PCT component after a course of anabolic steroids according to the proposed scheme for 2 weeks, instead of gonadotropin.

The use of gonadorelin spray in hormone replacement therapy
The proposed technique consists in intranasal administration of the gonadorelin preparation into the body in a pulsating, close to physiological regime. With infertility in men, associated with a decrease in the synthesis of gonadotropins as a result of the use of steroids and drugs, with the help of gonadorelin, testicular growth, normal secretion of sex hormones and spermatogenesis can be achieved. All of the above demonstrates the need to expand treatment options for men with hypogonadism. The lack of aromatization is also a great benefit of using the drug. It is this side effect that is most common when undergoing a course of hormone replacement therapy with testosterone. The proposed method for the complex treatment of hypgonadotropic infertility in men (the introduction of gonadorelin in a low dosage, intranasally in a pulsating mode Spray gonadorelin is prescribed during the day, after 60/90 minutes, one injection alternately in the nasal passage. On average, 10 times a day.) Restores the synthesis of LH and FSH. , stimulates the growth of the vas deferens, increases the level of testosterone in the blood, thereby ensuring the process of maturation of spermatozoa, shortens the duration of the treatment, is not necessary for staying in the hospital, is convenient in household use, if the rules of use are observed, it does not have harmful side effects on the body, does not has significant contraindications for use.

Side effects:
The following side effects of gonadorelin have been reported:

Suppression of the hypothalamus-pituitary axis of the testicles with the wrong regimen;
Headache;
Bone pain;
Nausea, diarrhea;
Allergic reactions.